The Inscription preserved on the marble architrave above the main entrance into the naos of Nerězi informs us, that the church in Nerězi was dedicated to St. Panteleimon and decorated at the expense of Alexios Angelos Komnenos in September of the thirteenth indiction of the year 1164, when the hegumenos was the monk Ioannikos (Ἐκαλλιεργήθη ὁ ναὸς τοῦ ἁγίου καὶ ἐνδόξου μεγαλομάρτυρος Παντελεήμονος ἐκ συνδρομῆς κυροῦ Ἀλεξίου τοῦ Κομνηνοῦ καὶ υἱοῦ τῆς πορφυρογεννήτης κυρᾶς Θεοδώρας μηνὶ Σεπτεμβρίῳ ἰνδικτιῶνος ῖγ ἔτους ΣΧΟΓ ἡγουμενεύοντος Ἰωαννικίου μοναχοῦ). The village Vodno donated by the king Stefan Uroš II Milutin to the Monastery of Saint George-Gorg formed a communal unit with the village of Nerězi and shared together the vineyards, the fields, the watermills, the hay harvests, the hunting and fishing grounds, meadows and all rights (Edno bo jestь selo Vodno i Nerězi sь vinogradi, sь nivijemь, sь voděničijemь, sь sěnokosi, sь lovišti zvěrnimi i sь ribnimi, sь zaběli i sь vsěmi pravinami ihь). These church properties in Vodno and Nerězi were administred as pronoia ( Takožde i po vsěhь selěhь crьkьvnihь vo Vodně i v Nerězihь, ponieže crьkovna pronija jestь, a ne ničija baština).