Born after 1288. Died in autumn 1325 or in winter 1326. Πανυπερσέβαστος in 1305, καῖσαρ 1326. Governor of Thessalonike in 1325/1326. Probably also governor of other towns in Macedonia. He was the nephew of the Byzantine Emperor Andronikos II Palaiologos and the cousin of Michael IX Palaiologos. His father was Palaiologos Konstantinos. His mother was Raulaina, Eirene Palaiologina. He was the husband of Eirene, kaisarissa, the daughter of Theodoros Metochites, since 1305/1306. His daughter Maria, born around 1313–1314, married in 1325–1326 the Serbian King Stefan Uroš III Dečanski. His son, whose name is unknown, held the rank of protosebastos and fell in the battle against the Bulgars near Rhosokastron in 1332. Mentioned in horismos of the Byzantine Emperor Andronikos III. from august 1321. Andronikos III. confirmed, that he is not the owner of the abandoned village Pungion. He rebelled against the Byzantine Emperor Andronikos II before 1326. His aim was to govern the western parts of the empire and Macedonia independently. He plotted with his brothers-in-law, the governors of Melnik and Strumica and asked also his son-in-law Stefan Uroš III. Dečanski for help. They plundered together Macedonia and reached the river Strymon and the town Serres. Andronikos II. offered him the insignia of a καῖσαρ, in order to end the revolt. He received the embassy of Andronikos II. in Skopje. He accepted the offer and promised to keep the peace. He also wanted to go back to Thessalonike, but died soon after an illness in Skopje. Both Manuel Philes and Theodoros Metochites composed an epitaph for him.