Mentioned in the appointment deed from the period between 1301 and 1361. The source denotes him as a κῦρ. He was hieromonk, then Abbot of the Monastery of the Holy Mother of God Spelaiotissa in Melnik. A not named patriarch appointed Meletios as Abbot of the Monastery of the Holy Mother of God Spelaiotissa in the upper town of Melnik (Ἡ μετριότης ἡμῶν διὰ τοῦ παρόντος αὐτῆς γράμματος παρακελεύεται εἶναι τὸν τιμιώτατον ἱερομόναχον κῦρ Μελέτιον εἰς καθηγούμενον τῆς ἐν τῷ θεοσώστω κάσ̣τ̣ρῳ τοῦ Μελενίκου διακειμένης σεβασμίας μονῆς τῆς ὑπεράγνου δεσποίνης καὶ Θεομη̣τορος καὶ ἐπικεκλημένης τοῦ Σπηλαίου).