Mentioned in the inscription from 1288/1289 on the door lintel of the esonarthex in the Church of the Holy Mother of God Pantanassa in Melnik. He appears as a κύρος in the inscription. He was a monk. He erected the Monastery Church of the Holy Mother of God Pantanassa in Melnik. He was also responsible for the fresco decoration of the interior of the church (ἀνηγέρθη ἐκ βάθρου καὶ ἀνιστορίθη ὁ θεῖος καὶ πάνσεπτος ναὸς τῆς πανάγνου Θεομήτορος τῆς Παντανάσης διὰ συνδρομῆς καὶ ἐξόδου κηροῦ μοναχοῦ Μακαρίου τοῦ Πο[...] ἐπὶ τῆ ποληχρονοίο χαρᾶ τοῦ κρατεοῦ καὶ ἁγίου ἡμῶν αὐθέντου μεγάλου βασιλέος Ἀνδρονίκου καὶ αὐτοκράτορος Κομνηνοῦ τοῦ Παλεολόγου καὶ Ήρήνης τῆς εὐσεβεστάτης αὐγούστης ἔτους ςψϛζ ἐντικτιῶνος β).