Mentioned in the sources from 1343 to 1353. He was the Abbot (igumen) of the Monastery of the Holy Virgin in Htětovo. He was the petitioner, who asked the Serbian King Stefan Uroš IV Dušan and Uroš, the Young King, to issue the chrysobull charter for the Monastery of the Holy Virgin in Htětovo (Si hrusovulь uspomenutijemь grěš’nago črnoriz’ca Arsenija, igumena htětovьskaago napisa gospodinь kralь Stepanь sь synom’ si Urošemь). It is obvious that Arsenije was Abbot of the monastery at the time, when the Serbian King Stefan Uroš IV Dušan, together with his son, granted the chrysobull for the Monastery of the Holy Virgin in Htětovo. He is probably identical with the Bishop of Zletovo, Arsenij, who is mentioned in the Lesnovo manuscript of Ephrem the Syrianʼs paraenesis from 1353 (poneže ne běh pisьcъ, nja povelěnïemь gospodina mi episkopa Arsenïa načrьtoh sih knigь). Arsenij was portrayed on the painting in the narthex of the Monastery of Archangel Michael in Lesnovo.