Mentioned in the chrysobull charter of the Serbian Emperor Stefan Uroš IV Dušan for the Esphigmenu Monastery from December 1347. He owned one-third of the village Krusobos with the place called Bysina, which was previously in the possession of the Esphigmenu Monastery and taken away from the monks in the course of a cadastral survey. The Serbian Emperor Stefan Uroš IV Dušan returned the properties of Pharmakes to the monks of the Esphigmenu Monastery in December 1347 (μετόχιον τὸ λεγόμενον Κρόσουβον μετὰ πάσης τῆς νομῆς καὶ περιοχῆς αὐτοῦ καὶ τῶν ἑτέρων πάντων δικαίων καὶ προνομίων αὐτοῦ, ἤγουν παροίκων, χωραφίων, ἀμπελώνων καὶ τοῦ ὑδρομυλικοῦ ἐργαστηρίου, προαπεσπάσθησαν δὲ δι’ ἀπογραφικῆς καταστάσεως αἱ δύο μερίδες τοῦ τοιούτου χωρίου καὶ ἐδόθησαν ἡ μὲν μία μερὶς τῶ Γαβριηλοπούλω ἐκείνω, ἡ δὲ ἐτέρα τῶ Φαρμάκη μετὰ καὶ τῆς Βυσινᾶς).