Mentioned in the sources from June 1355 to 1379. He appears as ὑπέρτιμος or kyrь in the sources. He was the Metropolitan of Melnik (ὁ ταπεινὸς Μελενίκου καὶ ὑπέρτιμος Κύριλλος, dostolěpni i v’sečьstni prěōsvešten’ni mitropolitь bogozdan’nago grada Mel’nika). He attested the authenticity of the charter from June 1355 concerning the sale of a plot of land in Chomnos Stolos near Melnik. Before May 1356 he found the Church of Saint Nicholas in Melnik damaged. He restored the church, built a wall around it and a tower (kyrь Kirilь ō crьkvi svetago Nikoli čudotvor’ca Stožьskoga kako jestь naš’lь ōnuzi crьkvь svetago Nikoli Stož’koga porušenu, i ōnь ju jestь ōbnovilь i sьzidalь i ōšte i k’tomu pirьgь sьzidalь svoimь trudomь i ōtkupomь). The Serbian Emperor Stefan Uroš V confirmed in a chrysobull in May 1356, together with his mother, the Empress Jelena-Jelisaveta, the possession of the Church of Saint Nicholas in the town of Melnik with its landed property and holdings in Psalině and Gr’dali to the Metropolitan Kirilь. The Serbian Emperor Stefan Uroš V donated also the village Smilovo to him (I za tozi uspomenutije prěōsvešten’nago ni mitropolita kyrь Kirila prije gospožda mi i mati carьstva mi carica kyra Jelisaf’ti i carьstvo mi, i darovasmo mu ōnuzi kjeliju, crьkvь svetago Nikoli Stožьs’koga i pirьgь što si estь samь zidalь sь vsěmi pravinami i s selomь što si estь drьžala tazi crьkvь, i s planinomь. I zapisa mu carьstvo mi Kondarata sь stasiōmь i s perivoljemь i s vinogradomь i s nivijemь što si estь drьžalь i prěgje u Psalině. I staьs Jullianova u Grdali na čemь jestь sědělь Svinoglavь sь v’sěmi pravinami stasi těh’zi. I ōšte se carьstvo mi zьgovori z gospoždomь caricomь materiju carьstva mi i pridados’mo selo Smilovo sь vsьmi pravinami i s megjami i sь zasel’ci kako su drьžali vlasteličiki carьstva mi v’se čisto. I ošte mu zapisa carьstvo mi vinograd Tukarevь i Luv’rov što mu su darovali vlasteličiki carьstva mi Vitomirь i Staniša. I kupeničije što si jestь kupilь samь mitropolitь Kyrilь i priložil pod ōnuzi crьkvь da mu něstь vol’nь nikto potvoriti). Kyrillos is mentioned in the patriarchal decree from 1379 concerning the property dispute of the Spelaion-Monastery.